Author’s response to reviews Title: Effectiveness of Direct-Acting Antiviral Therapy for Hepatitis C in Difficult-to-Treat Patients in a Safety-Net Health System: A Retrospective Cohort Study Authors:
نویسندگان
چکیده
Title: Effectiveness of Direct-Acting Antiviral Therapy for Hepatitis C in Difficult-to-Treat Patients in a Safety-Net Health System: A Retrospective Cohort Study Authors: Christina Yek ([email protected]) Carolina de la Flor ([email protected]) John Marshall ([email protected]) Cindy Zoellner ([email protected]) Grace Thomphson ([email protected]) Lisa Quirk ([email protected]) Christian Mayorga ([email protected]) Barbara Turner ([email protected]) Amit Singal ([email protected]) Mamta Jain ([email protected]) Version: 1 Date: 12 Oct 2017 Author’s response to reviews: Dear Dr Recchioni,
منابع مشابه
Effectiveness of direct-acting antiviral therapy for hepatitis C in difficult-to-treat patients in a safety-net health system: a retrospective cohort study
BACKGROUND Direct-acting antivirals (DAAs) have revolutionized chronic hepatitis C (HCV) treatment, but real-world effectiveness among vulnerable populations, including uninsured patients, is lacking. This study was conducted to characterize the effectiveness of DAAs in a socioeconomically disadvantaged and underinsured patient cohort. METHODS This retrospective observational study included a...
متن کاملNew treatment of hepatitis C (Direct Acting Antiviral)
Hepatitis C virus (HCV) infection is a major cause of chronic liver disease, with approximately 71 million chronically infected individuals worldwide. Clinical care for the patients with HCV-related liver disease has advanced considerably thanks to an enhanced understanding of the pathophysiology of the disease, and because of developments in diagnostic procedures and improvements in therapy an...
متن کاملDetection of Pre-treatment mutations leading to resistance to direct hepatitis C virus blocking drugs in patients with chronic hepatitis C
Background and objective: Human is the only host of hepatitis C virus. This virus has a positive single stranded RNA and lipoprotein envelop that has 7 confirmed genotypes. According to studies, genotypes 1a, 3a and 1b are the most common genotypes in Iran. No effective vaccine against HCV infection has been developed instead, advances in antiviral treatment using drugs that directly affect spe...
متن کاملSafety and Efficacy of Pegylated Interferon Alfa-2a for the Treatment of Hepatitis C in Patients with Major Thalassemia
Background: Hepatitis C virus (HCV) infection is the most common transfusion transmitted disease in poly-transfused patients worldwide. In this study we aimed to evaluate the effects of pegylated interferon alfa-2a (PEG-IFN A-2a) in reducing serum ALT and eradicating serum hepatitis C virus (HCV) RNA in HCV infected polytransfused thalassemic patients. Materials and Methods: A cohort of 51 HCV-...
متن کاملImmunological Response and Prevalence of Occult HCV Genotype 4 Among Patients Receiving Direct-Acting Antiviral (DAA) Drugs: A Cross-sectional Study
Background and Objective: Infection with the hepatitis C virus (HCV) is an endemic public health problem with long-term consequences, especially in Egypt. Egypt has one of the highest incidence rates of HCV worldwide. The current cross-sectional study aims to determine how prevalent occult HCV infection is and how it affects the individual's immune response. Methods: The studied adult patient...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017